Rootwork

Licorice

Glycyrrhiza glabra

FabaceaeMediterranean region, western Asia, and southern Russia

Description

overall appearance

Perennial herb growing 3-7 feet tall with pinnately compound leaves and purple to blue pea-like flowers; develops extensive underground stolons.

roots

Extensive underground root system with thick, woody main roots and numerous runners (stolons); roots are brown externally, yellow internally, and intensely sweet.

stem

Erect, branching stems that are green and smooth; stems can become somewhat woody at the base and support multiple branches.

leaves

Alternate, pinnately compound leaves with 9-17 oval leaflets; leaflets are 1-2 inches long, dark green above, and slightly sticky to the touch.

flowers

Small, purple to blue pea-like flowers arranged in dense, upright spikes 2-6 inches long; flowers bloom from June to July.

fruits/seeds

Small, brown, inflated pods containing 2-5 kidney-shaped seeds; pods are covered with hooked spines and ripen in late summer.

Active Compounds

Triterpene saponins (glycyrrhizin, glycyrrhizinic acid)Flavonoids (liquiritigenin, isoliquiritigenin, glabridin)Isoflavones (formononetin, glabrone)Coumarins and chalconesPolysaccharides and asparagineEssential oils and resin

Traditional Uses

  • Respiratory conditions (coughs, bronchitis, asthma)
  • Digestive disorders (gastritis, ulcers, constipation)
  • Adrenal exhaustion and chronic fatigue
  • Liver protection and detoxification
  • Inflammatory conditions and arthritis
  • Skin conditions (eczema, dermatitis)
  • Throat infections and voice loss

Modern Applications

  • Peptic ulcer treatment and gastric protection
  • Hepatitis and liver disease support
  • Addison's disease and adrenal insufficiency
  • Chronic fatigue syndrome management
  • Upper respiratory infection treatment
  • Anti-inflammatory effects for arthritis
  • Menopausal symptom relief

⚠️ Safety Information

Contraindications

  • High blood pressure (hypertension)
  • Heart disease and cardiac arrhythmias
  • Kidney disease and fluid retention
  • Pregnancy and breastfeeding
  • Liver cirrhosis and severe liver disease

Side Effects

  • Elevated blood pressure and sodium retention
  • Potassium depletion and muscle weakness
  • Fluid retention and edema
  • Headache and fatigue with long-term use
  • Possible hormonal effects (pseudoaldosteronism)

Drug Interactions

  • Blood pressure medications (may counteract effects)
  • Diuretics (may cause potassium loss)
  • Digoxin (increased toxicity risk)
  • Corticosteroids (may enhance effects)
  • Blood-thinning medications

Parts Used

  • Roots and stolons (primary medicinal part)
  • Occasionally aerial parts in traditional preparations

Preparation Methods

1-3 teaspoons dried root per cup water, simmer 15-20 minutes

1-2 teaspoons powdered root per cup hot water, steep 10 minutes

1:5 ratio in 20% alcohol, 2-5 ml three times daily

Concentrated decoction with honey for cough relief

1-4 grams powdered root daily

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Disclaimer: For educational purposes only. This is not medical advice. Always consult a qualified healthcare provider.